Xarelto (Rivaroxaban) 20mg Tablet (Click Here)
Pulmonary Embolism (PE) Treatment
– 15 mg by mouth every 12 hour for 21 days with food
THEN
– 20 mg by mouth daily
Deep Vein Thrombosis (DVT) Treatment
– 15 mg by mouth every 12 hour for 21 days with food
THEN,
– 20 mg by mouth daily
Reduction in Risk of Recurrence of DVT or PE
– 10 mg by mouth once daily with or without food, after at least 6 months of standard anticoagulant treatment
Reduction of Risk of Major Cardiovascular Events
– 2.5 mg by mouth twice daily, plus aspirin (75-100 mg) daily with or without food
Non-valvular Atrial Fibrillation
– 20 mg by mouth once daily with the evening meal
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Administration
– Administer doses ≥15 mg/day with food; dose of 10 mg/day may be administered without regard to meals.
– For nonvalvular atrial fibrillation, administer with the evening meal.
– For patients who cannot swallow whole tablets, the tablets (all strengths) may be crushed and mixed with applesauce immediately prior to use; immediately follow administration of the 15 mg and 20 mg tablets with food (10 mg tablets may be administered without regards to food).
Monitoring
– CBC with differential
– Renal function prior to initiation, when clinically indicated, and at least annually
– Hepatic function