Opdualag (Nivolumab-Relatlimab), for the Treatment of Melanoma

Melanoma
Unresectable or Metastatic
– 480mg/160mg IV every 4 weeks
– Continue until disease progression or unacceptable toxicity occurs
Infusion-related Reactions
Grade 1 or 2
– Interrupt or slow infusion rate
Grade 3 or 4
– Permanently discontinue
Females of Reproductive Potential
– Use effective contraception during treatment with nivolumab and for at least 5 months following last dose of therapy
IV Administration
– Administer the infusion over 30 minutes through an intravenous line containing a sterile, non-pyrogenic, low protein binding in-line polyethersulfone (PES), nylon, or polyvinylidene fluoride (PVDF) filter (pore size of 0.2 micrometer to 1.2 micrometer).
– Flush the intravenous line at the end of the infusion.
– Do not co-administer other drugs through the same IV line