Leqvio (Inclisiran) 284mg Prefilled Syringe: Instructions for Use (SC Injection)

Step 1. Inspect the pre-filled syringe

There may be air bubbles in the liquid. This is normal. Do not attempt to remove the air.

  • Do not use the pre-filled syringe if it looks damaged or if any of the solution for injection has leaked out of the pre-filled syringe.

Step 2. Remove the needle cap

Pull the needle cap straight off the pre-filled syringe. There may be a drop on the tip of the needle. This is normal.
Do not put the needle cap back on. Discard the needle cap.

Step 3. Insert the needle

Gently pinch the skin at the injection site and hold firmly throughout the injection. Insert the needle into the skin with the other hand at approximately a 45 degree angle as shown.

Step 4. Start the injection

Continue to pinch the skin. Slowly push the plunger down as far as it will go . This ensures that the entire dose is injected

Step 5. Complete the injection

Check that the piston head is seated between the needle shield wings as shown. This ensures that the needle shield has been activated and will cover the needle after the injection is complete.

Step 6. Release the plunger

Hold the pre-filled syringe at the injection site and slowly release the plunger until the needle is covered by the needle shield. Remove the pre-filled syringe from the injection site.

Step 7. Throw away the pre-filled syringe

Dispose of the pre-filled syringe in accordance with local requirements.