Description
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Administration
– May be administered SC (chemotherapy-induced neutropenia, peripheral blood progenitor cell collection, severe chronic neutropenia, hematopoietic radiation injury syndrome)
– Administer into the outer upper arm, abdomen (except within 2 inches of navel), front middle thigh, or the upper outer buttocks area
– Rotate injection site; do not inject into areas that are tender, red, bruised, hardened, or scarred, or sites with stretch marks.
– Some patients (or caregivers) may be appropriate candidates for SC self-administration with proper training; patients/caregivers should follow the manufacturer instructions for preparation and administration
– Do not skip doses, change schedule, or discontinue without consulting with health care provider.
– If filgrastim comes in contact with the skin, wash area thoroughly with soap and water; if eye contact occurs, flush exposed eye(s) with water.
Storage
– Store prefilled syringes at 2°C to 8°C (36°F to 46°F)
– Protect from light
– Do not shake
– May be removed from 2°C to 8°C (36°F to 46°F) storage for a single period of up to 5 days between 23°C to 27°C (73°F to 81°F)
– If not used within 5 days, the product may be returned to 2°C to 8°C (36°F to 46°F) up to the expiration date
– Dispose of syringes if stored at room temperature for more than 5 days
– Exposure to -1°C to -5°C (23°F to 30°F) for up to 72 hours and temperatures as low as -15°C to -25°C (5°F to -13°F) for up to 24 hours do not adversely affect stability
– Discard unused product