{"id":7542,"date":"2022-04-09T16:44:37","date_gmt":"2022-04-10T00:44:37","guid":{"rendered":"https:\/\/store.apotheraspecialtypharmacy.com\/?p=7542"},"modified":"2022-04-10T11:11:54","modified_gmt":"2022-04-10T19:11:54","slug":"drug-information-for-paxlovid-nirmatrelvir-ritonavir-oral-medications-for-the-treatment-of-mild-to-moderate-covid-19-available-on-apothera-clinical-decision-support-mobile-application","status":"publish","type":"post","link":"https:\/\/store.apotheraspecialtypharmacy.com\/?p=7542","title":{"rendered":"Drug Information for Paxlovid (Nirmatrelvir-Ritonavir), Oral Medications for the Treatment of Mild-to-Moderate COVID-19, Available on ApoThera Clinical Decision Support Mobile Application"},"content":{"rendered":"<p><strong><a href=\"http:\/\/www.ApoThera.com\">Drug Info: <em>ApoThera Drug Disease Clinical Support App<\/em><\/a><\/strong><\/p>\n<div dir=\"ltr\" data-setdir=\"false\"><strong>Nirmatrelvir-Ritonavir (Paxlovid)<\/strong><\/div>\n<div dir=\"ltr\" data-setdir=\"false\">\n<div>&#8211; 300 mg nirmatrelvir + 100 mg Ritonavir by mouth twice daily x 5 days<\/div>\n<div>&#8211; Initiate as soon as possible after COVID-19 diagnosis and within 5 days of symptom onset<\/div>\n<div><\/div>\n<div>&#8211; Completing the full 5-day treatment course and isolate in accordance with public health recommendations are important to maximize viral clearance and minimize viral transmission<\/div>\n<div><\/div>\n<div>&#8211; If patient is hospitalized due to severe or critical COVID-19 after starting treatment with nirmatrelvir\/ritonavir, completion of the full 5-day treatment is at the healthcare provider\u2019s discretion<\/div>\n<div><\/div>\n<div><strong>Missed Dose \u22648 hours<\/strong><\/div>\n<div>&#8211; Take missed dose as soon as possible, and resume normal dosing schedule<\/div>\n<div><\/div>\n<div dir=\"ltr\" data-setdir=\"false\"><strong>Missed Dose &gt;8 hours<\/strong><\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Skip dose, and take the next dose at the regularly scheduled time<\/div>\n<div>&#8211; Do not double dose to make up for missed dose<\/div>\n<div><\/div>\n<div><strong>Contraception<\/strong><\/div>\n<div>&#8211; Use of ritonavir may reduce efficacy of combined hormonal contraceptives<\/div>\n<div>&#8211; Advise patients using combined hormonal contraceptives to use an effective alternative contraceptive method or an additional barrier method of contraception<\/div>\n<div><\/div>\n<div><strong>Limitations of Use<\/strong><\/div>\n<div>&#8211; Not authorized for initiation of treatment in patients requiring hospitalization owing to severe or critical COVID-19<\/div>\n<div>&#8211; Not authorized for pre-exposure or post-exposure prophylaxis for prevention of COVID-19<\/div>\n<div>&#8211; Not authorized for &gt;5 consecutive days<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Drug Info: ApoThera Drug Disease Clinical Support App Nirmatrelvir-Ritonavir (Paxlovid) &#8211; 300 mg nirmatrelvir + 100 mg Ritonavir by mouth twice daily x 5 days &#8211; Initiate as soon as&hellip;<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[16],"tags":[268,269,270,367,366,368,371],"class_list":["post-7542","post","type-post","status-publish","format-standard","hentry","category-blog","tag-covid","tag-covid-19","tag-covid19","tag-nirmatrelvir","tag-paxlovid","tag-ritonavir","tag-sars-cov-2"],"jetpack_featured_media_url":"","jetpack-related-posts":[{"id":7537,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?p=7537","url_meta":{"origin":7542,"position":0},"title":"Drug Info for Lagevrio (Molnupiravir), Oral Medication for the Treatment of Mild-to-Moderate COVID-19, Available on ApoThera Clinical Decision Support Mobile Application","date":"April 9, 2022","format":false,"excerpt":"Drug Information for Oral Medications for the Treatment of Mild-to-Moderate COVID-19, Paxlovid (Nirmatrelvir-Ritonavir) and Molnupiravir (Lagevrio), Available on ApoThera Clinical Decision Support Mobile Application Drug Info: ApoThera Drug Disease Clinical Support App Molnupiravir (Lagevrio) - 800 mg (four 200-mg capsules) by mouth every 12 hours x 5 days - Treatment\u2026","rel":"","context":"In &quot;Blog&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":7374,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?p=7374","url_meta":{"origin":7542,"position":1},"title":"FDA Pulls Authorization for GSK-Vir&#8217;s COVID Therapy, Sotrovimab, as BA.2 Cases Rise","date":"April 6, 2022","format":false,"excerpt":"The U.S. health regulator said on Tuesday GlaxoSmithKline (GSK.L) and Vir Biotechnology's (VIR.O) antibody therapy was no longer authorized as a COVID-19 treatment, with data suggesting it was unlikely to be effective against the dominant Omicron sub-variant in the country. 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