{"id":32083,"date":"2025-12-08T13:45:50","date_gmt":"2025-12-08T21:45:50","guid":{"rendered":"https:\/\/store.apotheraspecialtypharmacy.com\/?post_type=product&#038;p=32083"},"modified":"2025-12-09T10:16:48","modified_gmt":"2025-12-09T18:16:48","slug":"avastin-single-dose-vials-100mg-iv-injection-bevacizumab-single-dose-vials-100mg-iv-injection-apothera-concierge-specialty-pharmacy","status":"publish","type":"product","link":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=avastin-single-dose-vials-100mg-iv-injection-bevacizumab-single-dose-vials-100mg-iv-injection-apothera-concierge-specialty-pharmacy","title":{"rendered":"Avastin Single Dose Vials 100mg IV Injection (Bevacizumab Single Dose Vials 100mg IV Injection) | ApoThera &#8211; Concierge Specialty Pharmacy"},"content":{"rendered":"<p><strong><a href=\"https:\/\/apps.apple.com\/us\/app\/apothera\/id526613282\">Drug Info:<em> ApoThera Drug Disease Clinical Support App<\/em><\/a><\/strong><\/p>\n<div>\n<div dir=\"ltr\" data-setdir=\"false\">\n<div><b><span style=\"color: #9d1811;\"><strong>IV Administration<\/strong><\/span><\/b><\/div>\n<div>&#8211; Infuse the initial dose over 90 minutes.<\/div>\n<div>&#8211; The second infusion may be shortened to 60 minutes if the initial infusion is well tolerated.<\/div>\n<div>&#8211; The third and subsequent infusions may be shortened to 30 minutes if the 60-minute infusion is well tolerated.<\/div>\n<div>&#8211; After tolerance at the 90-, 60-, and 30-minute infusion rates has been established, some institutions use an off-label 10-minute infusion rate (0.5 mg\/kg\/minute) in adults for bevacizumab dosed at 5 mg\/kg<\/div>\n<div>&#8211; In a study evaluating the safety of the 0.5 mg\/kg\/minute infusion rate, proteinuria, and hypertension incidences were not increased with the shorter infusion time.<\/div>\n<div>&#8211; Monitor closely during the infusion for signs\/symptoms of an infusion reaction.<\/div>\n<div>&#8211; Do not administer IV push or bolus.<\/div>\n<div>&#8211; Do not administer with dextrose solutions.<\/div>\n<div>&#8211; Temporarily withhold bevacizumab for 4 weeks prior to elective surgery and for at least 4 weeks (and until the surgical incision is fully healed) after surgery.<\/div>\n<\/div>\n<div>\n<div dir=\"ltr\" data-setdir=\"false\">\n<div dir=\"ltr\" data-setdir=\"false\">\n<div><em><b><span style=\"color: #9d1811;\"><strong>IV Reconstitution\u00a0<\/strong><\/span><\/b><\/em><\/div>\n<div>&#8211; Dilute in 100 mL NS prior to infusion (the manufacturer recommends a total volume of 100 mL).<br \/>\n&#8211; Do not mix with dextrose-containing solutions<\/div>\n<div><b>\u00a0<\/b><\/div>\n<div><b><span style=\"color: #9d1811;\"><strong>Storage<\/strong><\/span><\/b><\/div>\n<div><b><i>Intact Vials<\/i><\/b><\/div>\n<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Store intact vials at 2\u00b0C to 8\u00b0C (36\u00b0F to 46\u00b0F) in original carton<br \/>\n&#8211; Do not freeze.<br \/>\n&#8211; Protect from light<br \/>\n&#8211; Do not shake.<\/div>\n<div dir=\"ltr\" data-setdir=\"false\"><b><i>IV Infusion Solutions<\/i><\/b><\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Solutions diluted in NS are stable for up to 8 hours under refrigeration.<br \/>\n&#8211; Discard unused portion of vial.<\/div>\n<div dir=\"ltr\" data-setdir=\"false\"><b>\u00a0<\/b><\/div>\n<div dir=\"ltr\" data-setdir=\"false\"><b><span style=\"color: #9d1811;\"><strong>Monitoring<\/strong><\/span><\/b><\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Monitor closely during the infusion for signs\/symptoms of an infusion reaction<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Monitor CBC with differential<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Signs\/symptoms of gastrointestinal perforation, fistula, or abscess (including abdominal pain, constipation, vomiting, and fever)<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Signs\/symptoms of bleeding, including hemoptysis, gastrointestinal, and\/or CNS bleeding, and\/or epistaxis<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Monitor blood pressure every 2 to 3 weeks; more frequently if hypertension develops during therapy. Continue to monitor blood pressure after discontinuing due to bevacizumab-induced hypertension<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">&#8211; Monitor for proteinuria\/nephrotic syndrome with urine dipstick; collect 24-hour urine in patients with \u22652+ reading. Monitor for signs\/symptoms of thromboembolism (arterial and venous).<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\" data-setdir=\"false\">\n<div>\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\" data-setdir=\"false\">\n<div>\n<div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Prescription Required<\/b><\/span><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Free Next Day Delivery to Anywhere in CA and NY<\/b><\/span><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Free Same Day Delivery within 50-Mile Radius of ApoThera<\/b><\/span><\/div>\n<\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Annual Concierge Pharmacy Membership Fee: $300\/year<\/b><\/span><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>&#8211;\u00a0 Same-Day Physician Appointments<br \/>\n<\/b><\/span><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>&#8211;\u00a0 Generic Medicines: Just $2 per Tablet\/Capsule<br \/>\n<\/b><\/span><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Accept Credit Cards, Apple Pay and Zelle<\/b><\/span><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Concierge Pharmacy; Do NOT Accept Insurance<br \/>\n<\/b><\/span><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u2013 Do NOT\u00a0accept\u00a0manufacturer coupons<\/b><\/span><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>\u00a0<\/b><\/span><\/div>\n<\/div>\n<div dir=\"ltr\"><b>\u00a0<\/b><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\"><i><b>1) Physicians may send E-Prescriptions (E-Scripts) to:<\/b><\/i><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\"><b><span style=\"color: #652191;\">ApoThera<\/span><\/b><\/div>\n<div dir=\"ltr\"><em><b><span style=\"color: #652191;\">45 Post, 2nd Floor<\/span><\/b><\/em><\/div>\n<div dir=\"ltr\"><em><b><span style=\"color: #652191;\">Irvine, CA 92618<\/span><\/b><\/em><\/div>\n<div dir=\"ltr\"><em><b><span style=\"color: #652191;\">Phone: (949)387-7711<\/span><\/b><\/em><\/div>\n<div dir=\"ltr\"><em><b><span style=\"color: #652191;\">Fax:\u00a0 \u00a0 \u00a0(949)387-7712<\/span><\/b><\/em><\/div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\"><b>2) Alternatively, you may schedule an appointment with one of the physicians in the ApoThera Concierge Medicine Network.<\/b><\/div>\n<div dir=\"ltr\"><span style=\"color: #9d1811;\"><b>&#8211; Same-Day Physician Appointments:\u00a0<\/b><\/span>On-demand access to licensed physicians\u00a0in the ApoThera Concierge Network.<\/div>\n<div dir=\"ltr\"><b><strong><span style=\"color: #9d1811;\">\u00a0<\/span><\/strong><\/b><\/div>\n<div dir=\"ltr\"><b><strong><span style=\"color: #9d1811;\">\u00a0<\/span><\/strong><\/b><\/div>\n<div dir=\"ltr\"><b><strong><span style=\"color: #9d1811;\">\u00a0<\/span><\/strong><\/b><\/div>\n<div dir=\"ltr\"><\/div>\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div dir=\"ltr\">\n<div>\n<div dir=\"ltr\">\n<div dir=\"ltr\" data-setdir=\"false\">\n<div dir=\"ltr\" data-setdir=\"false\">\n<div>\n<div><b><span style=\"color: #9d1811;\">Endometrial Cancer<\/span><\/b><\/div>\n<div><b>Recurrent or Persistent<\/b><\/div>\n<div>&#8211; 15 mg\/kg every 3 weeks (as monotherapy) until disease progression or unacceptable toxicity<\/div>\n<\/div>\n<div dir=\"ltr\" data-setdir=\"false\">\n<div>\n<div><b><span style=\"color: #9d1811;\">Cervical Cancer<\/span><\/b><\/div>\n<div><b>Persistent\/Recurrent\/Metastatic<\/b><\/div>\n<div>&#8211; 15 mg\/kg IV every 3 weeks (in combination with paclitaxel and either cisplatin or topotecan) until disease progression or unacceptable toxicity<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div><\/div>\n<div><strong>Manufacturer: 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