{"id":3950,"date":"2021-12-15T17:17:15","date_gmt":"2021-12-16T01:17:15","guid":{"rendered":"http:\/\/54.151.78.1\/?post_type=product&p=3950"},"modified":"2025-02-18T13:26:44","modified_gmt":"2025-02-18T21:26:44","slug":"rinvoq-upadacitinib-15-mg-er-tablet","status":"publish","type":"product","link":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=rinvoq-upadacitinib-15-mg-er-tablet","title":{"rendered":"Rinvoq (Upadacitinib) 15mg ER Tablet"},"content":{"rendered":"
\n
Drug Info: ApoThera Drug Disease Clinical Support App<\/em><\/a><\/strong><\/div>\n<\/div>\n
<\/div>\n
\n
\n
Administration<\/strong><\/span><\/b><\/div>\n
– Take orally with or without food<\/div>\n
– Swallow tablet whole; do not split, crush, or chew<\/div>\n
\u00a0<\/strong><\/div>\n
Storage<\/strong><\/span><\/b><\/div>\n
– Store at 2-25\u00baC (36-77\u00baF)<\/div>\n
– Store in original bottle to protect from moisture<\/div>\n
\u00a0<\/b><\/div>\n
Monitoring<\/span><\/strong><\/div>\n<\/div>\n
\n
Neutropenia<\/strong><\/em><\/div>\n
– Evaluate neutrophil counts at baseline and thereafter according to routine patient management.<\/div>\n
– Avoid initiation of or interrupt treatment in patients with a low neutrophil count (ANC less than 1000 cells\/mm3<\/div>\n
Lymphopenia<\/strong><\/em><\/div>\n
– Evaluate lymphocyte counts at baseline and thereafter according to routine patient management.<\/div>\n
– Avoid initiation of or interrupt treatment in patients with a low lymphocyte count (less than 500 cells\/mm3)<\/div>\n
Anemia<\/strong><\/em><\/div>\n
– Decreases in hemoglobin levels to less than 8 g\/dL were reported in clinical studies.<\/div>\n
– Evaluate hemoglobin at baseline and thereafter according to routine patient management.<\/div>\n
– Avoid initiation of or interrupt treatment in patients with a low hemoglobin level (less than 8 g\/dL)<\/div>\n
Lipids<\/strong><\/em><\/div>\n
– Treatment was associated with increases in lipid parameters, including total<\/div>\n
cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol.<\/div>\n
– Elevations in LDL cholesterol decreased to pretreatment levels in response to statin therapy<\/div>\n
– The effect of these lipid parameter elevations on cardiovascular morbidity and mortality has not been determined.<\/div>\n
– Patients should be monitored 12 weeks after initiation of treatment, and thereafter according to the clinical guidelines for hyperlipidemia<\/div>\n
– Manage patients according to clinical guidelines for the management of hyperlipidemia.<\/div>\n
Liver Enzyme Elevations<\/strong><\/em><\/div>\n
– Treatment was associated with increased incidence of liver enzyme elevation<\/div>\n
compared to placebo.<\/div>\n
– Evaluate at baseline and thereafter according to routine patient management.<\/div>\n
– Prompt investigation of the cause of liver enzyme elevation is recommended to identify potential cases of drug-induced liver injury.<\/div>\n
– If increases in ALT or AST are observed during routine patient management and drug-induced liver injury is suspected, RINVOQ should be interrupted until this diagnosis is excluded.<\/div>\n
Embryo-Fetal Toxicity<\/strong><\/em><\/div>\n
– Based on findings in animal studies, it may cause fetal harm when administered to a pregnant woman.<\/div>\n
– Administration of upadacitinib to rats and rabbits during organogenesis caused<\/div>\n
increases in fetal malformations<\/div>\n
– Advise women of reproductive potential of the potential risk to<\/div>\n
a fetus and to use effective contraception during treatment with RINVOQ and for 4 weeks following completion of therapy<\/div>\n
Vaccination<\/strong><\/em><\/div>\n
– Use of live, attenuated vaccines during, or immediately prior to, therapy is not recommended<\/div>\n
– Prior to initiating of therapy, it is recommended that patients be brought up to date with all immunizations, including prophylactic zoster vaccinations, in agreement with current immunization guidelines<\/div>\n
\n
Find a Physician:<\/strong><\/div>\n
\n
Cedars Sinai Virtual Care<\/a><\/strong><\/em><\/div>\n
Cedars Sinai (Los Angeles)<\/a><\/strong><\/em><\/div>\n
Cottage Hospital Virtual Care (Santa Barbara)<\/a><\/strong><\/em><\/div>\n<\/div>\n
Hoag (Orange County)<\/a><\/strong><\/em><\/div>\n
Hoag Concierge Medicine (Newport Beach)<\/a><\/strong><\/em><\/div>\n
Hoag Urgent Care Telehealth<\/a><\/strong><\/em><\/div>\n
Pacific Rheumatology Center (Orange County)<\/a><\/strong><\/em><\/div>\n
\n
Providence Telehealth<\/a><\/strong><\/em><\/div>\n
Scripps Virtual Care (San Diego)<\/a><\/strong><\/em><\/div>\n<\/div>\n
West Dermatology (Newport Beach)<\/a><\/strong><\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Drug Info: ApoThera Drug Disease Clinical Support App<\/a><\/strong><\/p>\n

\n
\n
\n
\n
\n
\n
\n
Atopic Dermatitis<\/span><\/b><\/div>\n
Initial Dose<\/i><\/b><\/div>\n
– 15 mg by mouth once daily<\/div>\n
Maintenance Dose<\/i><\/b><\/div>\n
– May increase to 30 mg by mouth once daily if an adequate response is not achieved<\/div>\n
– Discontinue if 30-mg dose if adequate response not achieved<\/div>\n
– Use lowest effective dose needed to maintain response<\/div>\n
<\/div>\n<\/div>\n
Rheumatoid Arthritis<\/span><\/b><\/strong><\/div>\n
Initial Dose<\/i><\/b><\/div>\n
– 15 mg by mouth once daily<\/div>\n
Maintenance Dose<\/i><\/b><\/div>\n
– May be used as monotherapy or in combination with methotrexate or other non-biologic DMARDs<\/div>\n
<\/div>\n
Psoriatic Arthritis\u00a0<\/span><\/b><\/div>\n
– 15 mg by mouth once daily<\/div>\n
\u00a0<\/b><\/div>\n
\u2013 Rx Required<\/span><\/b><\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
\n
\n
\u2013 Free Overnight Shipping to CA and NY<\/span><\/b><\/div>\n
\u2013 No Shipping to Outside of CA and NY<\/span><\/b><\/div>\n<\/div>\n
\u2013 Accept FSA and HSA Cards<\/span><\/b><\/div>\n
\u2013 Accept Credit Cards (No Coupons)<\/span><\/b><\/div>\n
<\/div>\n<\/div>\n
Physicians may send E-Prescriptions (E-Scripts) to:<\/i>
\n<\/b><\/div>\n
\n
ApoThera<\/span><\/b><\/div>\n
45 Post Street, 2nd Floor<\/b><\/em><\/div>\n
Irvine, CA 92618<\/b><\/em><\/div>\n
Phone: (949)387-7711<\/b><\/em><\/div>\n
Fax:\u00a0 \u00a0 \u00a0\u00a0(949)387-7712<\/b><\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
\n
Manufacturer: <\/b>Abbvie<\/a><\/strong><\/em><\/div>\n
Rinvoq Medication Guide<\/a><\/strong><\/em><\/div>\n<\/div>\n","protected":false},"featured_media":12328,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false},"product_cat":[191],"product_tag":[17225,17226,17227,17228,17229,17230,17231,17232,17233,17251,17234,17235,17236,17237,17238,17239,17240,17241,17242,17243,17244,17245,17246,17247,17248,17249,17250,17191,613,17252],"class_list":{"0":"post-3950","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-arthritis","7":"product_tag-rinvoq-15-in-stock","8":"product_tag-rinvoq-15mg-in-balboa-peninsula","9":"product_tag-rinvoq-15mg-in-stock","10":"product_tag-rinvoq-15mg-in-stock-for-atopic-dermatitis","11":"product_tag-rinvoq-15mg-in-stock-for-eczema","12":"product_tag-rinvoq-15mg-in-stock-in-beverly-hills","13":"product_tag-rinvoq-15mg-in-stock-in-brentwood","14":"product_tag-rinvoq-15mg-in-stock-in-del-mar-heights","15":"product_tag-rinvoq-15mg-in-stock-in-fresno","16":"product_tag-rinvoq-15mg-in-stock-in-hollywood","17":"product_tag-rinvoq-15mg-in-stock-in-irvine","18":"product_tag-rinvoq-15mg-in-stock-in-long-island","19":"product_tag-rinvoq-15mg-in-stock-in-los-angeles","20":"product_tag-rinvoq-15mg-in-stock-in-manhattan","21":"product_tag-rinvoq-15mg-in-stock-in-new-york","22":"product_tag-rinvoq-15mg-in-stock-in-newport-beach","23":"product_tag-rinvoq-15mg-in-stock-in-newport-coast","24":"product_tag-rinvoq-15mg-in-stock-in-palm-springs","25":"product_tag-rinvoq-15mg-in-stock-in-rancho-bernardo","26":"product_tag-rinvoq-15mg-in-stock-in-rancho-santa-fe","27":"product_tag-rinvoq-15mg-in-stock-in-sacramento","28":"product_tag-rinvoq-15mg-in-stock-in-san-diego","29":"product_tag-rinvoq-15mg-in-stock-in-san-francisco","30":"product_tag-rinvoq-15mg-in-stock-in-santa-barbara","31":"product_tag-rinvoq-15mg-in-stock-in-santa-monica","32":"product_tag-rinvoq-15mg-in-stock-in-silicon-valley","33":"product_tag-rinvoq-15mg-in-stock-irvine","34":"product_tag-rinvoq-in-stock","35":"product_tag-upadacitinib","36":"product_tag-upadacitinib-15mg-in-stock","37":"wcpa_has_options","39":"first","40":"instock","41":"purchasable","42":"product-type-simple"},"jetpack-related-posts":[{"id":5566,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=rinvoq-upadacitinib-30-mg-er-tablet","url_meta":{"origin":3950,"position":0},"title":"Rinvoq (Upadacitinib) 30mg ER Tablet","date":"February 26, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Rheumatoid Arthritis Initial Dose - 15 mg by mouth once daily Maintenance Dose - May be used as monotherapy or in combination with methotrexate or other non-biologic DMARDs Psoriatic Arthritis\u00a0 - 15 mg by mouth once daily \u00a0 Atopic Dermatitis Initial Dose\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/store.apotheraspecialtypharmacy.com\/wp-content\/uploads\/2022\/02\/Rinvoq.30mg.ER_.jpg?fit=214%2C391&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":5026,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=promacta-eltrombopag-50mg-tablet","url_meta":{"origin":3950,"position":1},"title":"Promacta (Eltrombopag) 50mg Tablet","date":"February 13, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Chronic Immune (Idiopathic) Thrombocytopenia (ITP) Initial Dose - 50 mg by mouth once daily - 25 mg by mouth once daily for patients of East-Asian ethnicity Maintenance Dose - Dose should be titrated based on platelet response - Use the lowest dose\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":5038,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=promacta-eltrombopag-25mg-tablet","url_meta":{"origin":3950,"position":2},"title":"Promacta (Eltrombopag) 25mg Tablet","date":"February 13, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Chronic Immune (Idiopathic) Thrombocytopenia (ITP) Initial Dose - 50 mg by mouth once daily - 25 mg by mouth once daily for patients of East-Asian ethnicity Maintenance Dose - Dose should be titrated based on platelet response - Use the lowest dose\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":5830,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=corlanor-ivabradine-5mg-tablet","url_meta":{"origin":3950,"position":3},"title":"Corlanor (Ivabradine) 5mg Tablet","date":"March 5, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Congestive Heart Failure (CHF) Initial Dose \u2013 5 mg by mouth twice daily \u2013 2.5 mg by mouth twice daily in patients with a history of conduction defects or who may experience hemodynamic compromise due to bradycardia Maintenance Dose \u2013 After 2\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/store.apotheraspecialtypharmacy.com\/wp-content\/uploads\/2022\/03\/Corlanor.5mg.Tablet.Brand-2.jpg?fit=262%2C245&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":5836,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=corlanor-ivabradine-7-5mg-tablet","url_meta":{"origin":3950,"position":4},"title":"Corlanor (Ivabradine) 7.5mg Tablet","date":"March 5, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Congestive Heart Failure (CHF) Initial Dose \u2013 5 mg by mouth twice daily \u2013 2.5 mg by mouth twice daily in patients with a history of conduction defects or who may experience hemodynamic compromise due to bradycardia Maintenance Dose \u2013 After 2\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"https:\/\/i0.wp.com\/store.apotheraspecialtypharmacy.com\/wp-content\/uploads\/2022\/03\/Corlanor.7.5mg.Tablet.Brand-2.jpg?fit=252%2C243&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":5041,"url":"https:\/\/store.apotheraspecialtypharmacy.com\/?product=promacta-eltrombopag-12-5mg-tablet","url_meta":{"origin":3950,"position":5},"title":"Promacta (Eltrombopag) 12.5mg Tablet","date":"February 13, 2022","format":false,"excerpt":"Drug Info: ApoThera Drug Disease Clinical Support App Chronic Immune (Idiopathic) Thrombocytopenia (ITP) Initial Dose - 50 mg PO once daily - 25 mg once daily for patients of East-Asian ethnicity Maintenance Dose - Dose should be titrated based on platelet response - Use the lowest dose to achieve and\u2026","rel":"","context":"Similar post","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/product\/3950","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3950"}],"version-history":[{"count":20,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/product\/3950\/revisions"}],"predecessor-version":[{"id":12327,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/product\/3950\/revisions\/12327"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=\/wp\/v2\/media\/12328"}],"wp:attachment":[{"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3950"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=3950"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/store.apotheraspecialtypharmacy.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=3950"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}