Description
Drug Info: ApoThera Drug Disease Clinical Support App
Indications
– Used for chronic weight management in addition to reduced calorie diet and increased physical activity in adults, who have:
• a BMI of 30 kg/m2 or greater (with obesity), or
• a BMI of 27 kg/m2 and less than 30 kg/m2 (overweight) and weight-related health problems.
*BMI (Body Mass Index) is a measure of your weight in relation to your height measured.
Missed Dose
5 Days or Less
– Use it as soon as you remember.
-Then inject your next dose as usual on your scheduled day
More than 5 Days
– Skip the missed dose
– Then inject your next dose as usual on your scheduled day
– Do not take a double dose to make up for a missed dose
Storage
Intact SC Pens
– Store in the refrigerator at 2°C to 8°C (36-46°F)
– Storage in the original carton is recommended until time of administration in order to protect from light.
– Do not store in freezer or directly adjacent to the refrigerator cooling element
– Do not freeze and do not use if frozen
– If needed, each single-use pen, prior to cap removal, can be kept at a temperature, 46-86°F (8-30°C), for a total of 28 days.
– If your pen has been exposed to light or temperatures above 30°C (86°F), has been out of the refrigerator for more than 28 days, or has been frozen, dispose of it.
– Keep pen cap on when not in use
– Protect from excessive heat and sunlight
SC Administration
– Administer SC to abdomen, thigh, or upper arm
– The time of day and the injection site can be changed without dose adjustment
– Administer once weekly, on the same day each week, at any time of day, with or without meals
– Visually inspect before use; drug should appear clear and colorless
– Do not use semaglutide if particulate matter and coloration observed
Instructions for Wegovy SC Injection (Video)
Side Effects
Very Common: may affect more than 1 in 10 people
• feeling or being sick (nausea or vomiting)
• diarrhea
• constipation
• stomach pain
• feeling weak or tired
• headache
– these usually goes away over time
• feeling or being sick (nausea or vomiting)
• diarrhea
• constipation
• stomach pain
• feeling weak or tired
• headache
– these usually goes away over time
Common: may affect up to 1 in 10 people
• feeling dizzy
• upset stomach or indigestion
• burping
• gas (flatulence)
• bloating of the stomach
• inflamed stomach (‘gastritis’) – the signs include stomach-ache, feeling sick (nausea) or
being sick (vomiting)
• reflux or heartburn – also called ‘gastro-esophageal reflux disease’
• hair loss
• injection site reactions
• low blood sugar (hypoglycaemia) in patients with diabetes
• low blood pressure
• increase of pancreatic enzymes (such as lipase) shown in blood tests
• hemorrhoids
• upset stomach or indigestion
• burping
• gas (flatulence)
• bloating of the stomach
• inflamed stomach (‘gastritis’) – the signs include stomach-ache, feeling sick (nausea) or
being sick (vomiting)
• reflux or heartburn – also called ‘gastro-esophageal reflux disease’
• hair loss
• injection site reactions
• low blood sugar (hypoglycaemia) in patients with diabetes
• low blood pressure
• increase of pancreatic enzymes (such as lipase) shown in blood tests
• hemorrhoids
Uncommon: may affect up to 1 in 100 people
• fast heartbeat
• increase of pancreatic enzymes (such as amylase) shown in blood tests
• feeling faint or fainting/passing out
• low blood sugar (hypoglycaemia) in patients without diabetes
• fast heartbeat
• increase of pancreatic enzymes (such as amylase) shown in blood tests
• feeling faint or fainting/passing out
• low blood sugar (hypoglycaemia) in patients without diabetes
Children and Adolescents
– Not recommended in children and adolescents under 18 years of age as the safety and efficacy in this age group have not yet been studied.
Pregnancy and Breastfeeding
– Tell your doctor if you are pregnant, think you might be pregnant, or are planning to become pregnant.
– Tell your doctor if you are pregnant, think you might be pregnant, or are planning to become pregnant.
– Should not be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child.
– If you could become pregnant while using Wegovy™, it is recommended to use contraception
– Do not use this medicine if you are breast-feeding, because it is not known if it passes into breast milk
Digestive System and Dehydration
– You may experience feeling sick (nausea) or being sick (vomiting), and diarrhea.
– These side effects can cause dehydration (loss of fluids).
– It is therefore important to drink plenty of fluids to prevent dehydration.
– This is especially important if you have kidney problems.
– Talk to your doctor if you have any questions or concerns.
Diabetic Eye Disease (Retinopathy)
– This medication may cause a temporary worsening of diabetic eye disease.
– This medication may cause a temporary worsening of diabetic eye disease.
– If you have diabetic eye disease and experience eye or vision problems while taking this medication, talk to your doctor
Contraindications
• Have type 1 diabetes
• Have ever had diabetic ketoacidosis (increased ketones in the blood or urine)
• Have ever had an allergic reaction to OZEMPIC or RYBELSUS
• Have a high heart rate (fast pulse)
• Have ever had an inflamed pancreas (pancreatitis)
• Are breastfeeding or plan to breastfeed
• Are pregnant or plan to become pregnant
• Have end stage renal disease
• Have gastrointestinal (digestive) problems, including severe vomiting, diarrhea and/or dehydration
• Have hepatic (liver) disease
• Have diabetic eye disease (diabetic retinopathy)
• Have heart failure
• Have ever had gallbladder disease
• Have ever attempted suicide, or had suicidal thoughts or depression
Active Ingredient
– Semaglutide
Inactive Ingredients
– Disodium phosphate dihydrate
– Hydrochloric Acid
– Sodium Chloride
– Sodium hydroxide
– Water for injection
Find a Physician for Weight Loss (Wegovy 2.4mg):
