Description
Drug Info: ApoThera Drug Disease Clinical Support App
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SC Administration
– Administered SC once monthly by healthcare professional
– Total dose of 210 mg SC requires 2 separate 105-mg prefilled syringes (and 2 separate SC injections)
– Inject two 105-mg prefilled syringes, one after the other, in abdomen (except for 2-inch area around navel), thigh, or outer area of upper arm
Missed Dose
– Administer as soon as possible; thereafter, schedule doses once monthly from the date of the last dose
SC Preparation
– Remove 2 syringes from carton and visually inspect for particles and discoloration; solution should appear clear to opalescent, colorless to light yellow
– Do not use if solution is cloudy, discolored, or contains particles
– Do not use if syringe is cracked or broken, gray needle cap is missing or not securely attached, or passed the expiration date
– Always hold syringe by the barrel to remove from the tray; do not grasp by plunger rod or gray needle cap
– Do not remove gray needle cap until ready to inject
– Allow to sit at room temperature for at least 30 minutes before injecting; do not warm in any other way
– Clean injection site with alcohol wipes; let skin dry
– Choose different injection site for each injection; if same injection location, do not inject near previous injection site
– Do not inject in areas where skin is tender, bruised, red, or hard; avoid scars
Storage
– Refrigerate at 2-8°C (36-46°F) in the original carton to protect from light
– Do not freeze
– Do not shake
– If removed from refrigerator, can be kept at room temperature up to 25°C (77°F) in original carton and must be used within 30 days; if not used within 30 days, discard
– Do not expose to temperatures >25°C (77°F)